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fungal infection |
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fungal infection |
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Hypokalemia |
Hypokalemiam be a low level of atomic number 19 (K+) within the serum.Mild low atomic number 19 doesn't usually cause symptoms. Symptoms might embody feeling tired, leg cramps, weakness, and constipation. Low atomic number 19 additionally will increase the danger of Associate in Nursing abnormal regular recurrence, that is commonly too slow and might cause asystole.
Causes of symptom embody innate reflex, diarrhea, medications like Lasix and steroids, dialysis, diabetes, adenosis, hypomagnesemia, and not enough intake within the diet.[1] traditional atomic number 19 levels square measure between three.5 and 5.0 mmol/L (3.5 and 5.0 mEq/L) with levels below three.5 mmol/L outlined as symptom.[1][2] it's classified as severe once levels square measure but two.5 mmol/L.[1] Low levels may additionally be suspected supported Associate in Nursing EKG (ECG).[1] symptom may be a high level of atomic number 19 within the serum.[1]
The speed at that atomic number 19 ought to get replaced depends on whether or not or not there square measure symptoms or abnormalities on Associate in Nursing EKG.[1] atomic number 19 levels that square measure solely slightly below the traditional vary is managed with changes within the diet.[3] Lower levels of atomic number 19 need replacement with supplements either taken orally or given intravenously.[3] If given intravenously, atomic number 19 is usually replaced at rates of but twenty mmol/hour.[1] Solutions containing high concentrations of atomic number 19 (>40 mmol/L) ought to usually tend employing a central blood vessel tubing.[3] atomic number 12 replacement may additionally be needed.[1]
Hypokalemia is one in all the foremost common water–electrolyte imbalances.[4] It affects concerning 2 hundredth of individuals admitted to hospital.[4] The word "hypokalemia" comes from hypo- which means "under", kalium which means “potassium”, and -emia which means "condition of the blood".[5]
Signs and symptoms Edit
Mild symptom is commonly while not symptoms, though it should cause elevation of pressure,[6] and might provoke the event of Associate in Nursing abnormal regular recurrence. Severe symptom, with blood serum atomic number 19 concentrations of two.5–3 meq/l (Nl: three.5–5.0 meq/l), might cause muscle weakness, myalgia, tremor, and muscle cramps (owing to disturbed perform of skeletal muscle), and constipation (from disturbed perform of swish muscle). With additional severe symptom, nervous disorder and hyporeflexia might result. Reports exist of rhabdomyolysis occurring with profound symptom with blood serum atomic number 19 levels but two meq/l.
Respiratory depression from severe impairment of musculus perform is found in some individuals.
Causes Edit
Hypokalemia may end up from one or additional of those medical conditions:
Inadequate atomic number 19 intake Edit
Not ingestion a diet with enough potassium-containing foods or abstinence will cause the gradual onset of symptom. this can be a rare cause and should occur in those with anorexia or those on a ketogenic diet.
Gastrointestinal or skin loss Edit
A additional common cause is excessive loss of atomic number 19, typically related to serious fluid losses that "flush" atomic number 19 out of the body. Typically, this can be a consequence of looseness of the bowels, excessive perspiration, or losses related to muscle-crush injury, or surgical procedures. innate reflex may also cause symptom, though not a lot of atomic number 19 is lost from the excreta. Rather, serious urinary losses of K+ within the setting of post-emetic bicarbonaturia force urinary atomic number 19 excretion (see pathology below). different duct causes embody duct gland fistulae and therefore the presence of nonmalignant neoplasm.
Urinary loss Edit
Certain medications will cause excess atomic number 19 loss within the weewee. pressure medications like loop diuretics (e.g. furosemide) and diuretic diuretics (e.g. hydrochlorothiazide) unremarkably cause symptom. different medications like the antifungal antibiotic drug B or the antineoplastic cisplatin may also cause long symptom.
A special case of atomic number 19 loss happens with diabetic acidosis. symptom is determined with low total body atomic number 19 and a coffee animate thing concentration of atomic number 19. additionally to urinary losses from kidney disease and volume contraction, additionally Associate in Nursing obligate loss of atomic number 19 from urinary organ tubules happens as a ion partner to the charged organic compound, β-hydroxybutyrate.
A low level of atomic number 12 within the blood may also cause symptom. atomic number 12 is needed for adequate process of atomic number 19. this might become evident once symptom persists despite atomic number 19 supplementation. different solution abnormalities may additionally be gift.
An increase within the pH scale of the blood (alkalosis) will cause temporary symptom by inflicting a shift of atomic number 19 out of the plasma and opening fluids into the weewee via variety of reticulate mechanisms.
1) group B intercalated cells within the collection duct absorb H+ and secrete HCO3, whereas in type A intercalated cells protons square measure secreted via each H+-K+ATPases and H+ ATP-ases on the apical/luminal surface of the cell. By definition, the H+-K+ATPase reabsorbs one atomic number 19 particle into the cell for each nucleon it secretes into the lumen of the collection duct of a uriniferous tubule. additionally, once H+ is expelled from the cell (by H+ATP-ase), cations—in this case potassium—are preoccupied by the cell so as to keep up electroneutrality (but not through direct exchange like the H+-K+ATPase).[9] so as to correct the pH scale throughout pathology, these cells can use these mechanisms to absorb nice amounts of H+, which can concomitantly increase their animate thing concentrations of atomic number 19. This concentration gradient drives atomic number 19 to be secreted across the top surface of the cell into the hollow lumen through atomic number 19 channels (this expedited diffusion happens in each group B intercalated cells and Principal cells within the collection duct).
2) alkalosis is commonly gift in states of volume depletion, like innate reflex, thus atomic number 19 is additionally lost via aldosterone-mediated mechanisms.
3) throughout alkalosis, the acute rise of plasma HCO3− concentration (caused by innate reflex, for example) can exceed the capability of the urinary organ proximal tube to absorb this ion, Associate in Nursingd atomic number 19 are excreted as an obligate ion partner to the hydrogen carbonate.[10]
Disease states that cause abnormally high mineralocorticoid levels will cause cardiovascular disease and excessive urinary losses of atomic number 19.
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Cerebral edema |
Cerebral edema: Everything you wish to understand
Symptoms
Causes
Diagnosis
Treatment
Outlook
Cerebral hydrops is once fluid builds up round the brain, inflicting a rise in pressure called intracranial pressure.
Swelling or inflammation is a component of the body’s natural response to injury. hydrops refers to swelling thanks to at bay fluid, and it will happen anyplace within the body. If hydrops happens within the brain, however, it will cause severe complications.
Cerebral hydrops will limit the availability of blood to the brain. Blood carries gas to the brain, that the brain needs to operate. an absence of gas within the brain will harm brain cells or cause them to die.
Intracranial pressure (ICP) will have an effect on specific regions of the brain or the entire brain betting on the underlying cause.
Cerebral hydrops will cause irreversible harm and, in some cases, be fatal.
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More info
Cerebral edema: Everything you wish to understand
Medically reviewed by Seunggu dynasty, M.D. — Written by Aaron Kandola on July sixteen, 2018
Symptoms
Causes
Diagnosis
Treatment
Outlook
Cerebral hydrops is once fluid builds up round the brain, inflicting a rise in pressure called intracranial pressure.
Swelling or inflammation is a component of the body’s natural response to injury. hydrops refers to swelling thanks to at bay fluid, and it will happen anyplace within the body. If hydrops happens within the brain, however, it will cause severe complications.
Cerebral hydrops will limit the availability of blood to the brain. Blood carries gas to the brain, that the brain needs to operate. an absence of gas within the brain will harm brain cells or cause them to die.
Intracranial pressure (ICP) will have an effect on specific regions of the brain or the entire brain betting on the underlying cause.
Cerebral hydrops will cause irreversible harm and, in some cases, be fatal.
Symptoms
Cerebral hydrops may be a buildup of fluid round the brain.
Symptoms of cerebral hydrops might include:
a headache
nausea
vomiting
dizziness
memory issues
difficulty speaking
seizures
vision loss
neck pain
difficulty moving
loss of consciousness
The symptoms can vary betting on the severity and underlying reason for the swelling.
Causes
The ICP related to cerebral hydrops will have a variety of various causes, including:
Traumatic brain injury: A traumatic brain injury is AN acute trauma, like from a fall or vehicle accident.
Ischemic stroke: AN ischaemia happens once a grume restricts the flow of gas to the brain. an absence of gas will harm the brain cells and cause swelling and pressure.
Brain tumor: A tumour will press against different areas of the brain or stop fluid from departure the brain, inflicting elevated ICP.
Infection: Infections caused by microorganism or an outbreak will cause swelling within the brain. for instance, rubor is AN infection that causes inflammation within the brain, and elevated ICP might develop as a result.
Brain hemorrhage: A brain hemorrhage happens once a vas within the brain ruptures and leaks. This causes inflammation and a rise in ICP.
High altitude: Cerebral hydrops can even occur on top of altitudes of around four,000 meters.
Cerebral edema: Everything you wish to understand
Medically reviewed by Seunggu dynasty, M.D. — Written by Aaron Kandola on July sixteen, 2018
Symptoms
Causes
Diagnosis
Treatment
Outlook
Cerebral hydrops is once fluid builds up round the brain, inflicting a rise in pressure called intracranial pressure.
Swelling or inflammation is a component of the body’s natural response to injury. hydrops refers to swelling thanks to at bay fluid, and it will happen anyplace within the body. If hydrops happens within the brain, however, it will cause severe complications.
Cerebral hydrops will limit the availability of blood to the brain. Blood carries gas to the brain, that the brain needs to operate. an absence of gas within the brain will harm brain cells or cause them to die.
Intracranial pressure (ICP) will have an effect on specific regions of the brain or the entire brain betting on the underlying cause.
Cerebral hydrops will cause irreversible harm and, in some cases, be fatal.
Symptoms
Cerebral hydrops may be a buildup of fluid round the brain.
Symptoms of cerebral hydrops might include:
a headache
nausea
vomiting
dizziness
memory issues
difficulty speaking
seizures
vision loss
neck pain
difficulty moving
loss of consciousness
The symptoms can vary betting on the severity and underlying reason for the swelling.
Causes
The ICP related to cerebral hydrops will have a variety of various causes, including:
Traumatic brain injury: A traumatic brain injury is AN acute trauma, like from a fall or vehicle accident.
Ischemic stroke: AN ischaemia happens once a grume restricts the flow of gas to the brain. an absence of gas will harm the brain cells and cause swelling and pressure.
Brain tumor: A tumour will press against different areas of the brain or stop fluid from departure the brain, inflicting elevated ICP.
Infection: Infections caused by microorganism or an outbreak will cause swelling within the brain. for instance, rubor is AN infection that causes inflammation within the brain, and elevated ICP might develop as a result.
Brain hemorrhage: A brain hemorrhage happens once a vas within the brain ruptures and leaks. This causes inflammation and a rise in ICP.
High altitude: Cerebral hydrops can even occur on top of altitudes of around four,000 meters.
Diagnosis
Diagnosing cerebral hydrops may be difficult, as there area unit several potential causes and therefore the symptoms might vary significantly.
To make a diagnosing, a doctor might do:
a physical examination of the top and neck
a CT scan or MRI of the top
blood tests
a neurologic examination
Brain drain could be a slang term indicating substantial out-migration or migration of people. A drain may result from turmoil inside a nation, the existence of favorable skilled opportunities in different countries, or from a need to hunt the next commonplace of living. additionally to occurring geographically, drain could occur at the structure or industrial levels once employees understand higher pay, benefits, or upward quality inside another company or trade.
KEY TAKEAWAYS
Brain drain could be a slang term indicating substantial out-migration or migration of people.
Brain drain may result from many factors together with political turmoil or the existence of a lot of favorable skilled opportunities elsewhere.
Brain drain causes countries, industries, and organizations to lose a core portion of valuable people.
Understanding drain
Brain drain causes countries, industries, and organizations to lose a core portion of valuable people. The term typically describes the departure of teams of doctors, attention professionals, scientists, engineers, or monetary professionals. once these folks leave, their places of origin square measure injured in 2 main ways in which. First, experience is lost with every emigree, decreasing the availability of that profession. Secondly, the country's economy is injured as a result of every skilled represents surplus defrayment units. Professionals typically earn giant salaries, therefore their departure reduces shopper defrayment therein region or the country overall.
Geographic, structure, and Industrial drain
Brain drain, conjointly called a personality's capital flight, will occur on many levels. Geographic drain happens once proficient professionals fly the coop one country or region inside a rustic in favor of another. structure drain involves the mass exodus of proficient employees from a corporation, actually because they sense instability, an absence of chance inside the corporate, or they'll feel that they'll notice their career goals a lot of simply at another company. Industrial drain happens once ball-hawking employees exit not solely a corporation however a complete trade.
Geographic, structure, and Industrial drain
Brain drain, conjointly called a personality's capital flight, will occur on many levels. Geographic drain happens once proficient professionals fly the coop one country or region inside a rustic in favor of another. structure drain involves the mass exodus of proficient employees from a corporation, actually because they sense instability, an absence of chance inside the corporate, or they'll feel that they'll notice their career goals a lot of simply at another company. Industrial drain happens once ball-hawking employees exit not solely a corporation however a complete trade.
Real World Example of drain
As of 2019, drain has been a major consequence of the continuing Puerto Rican debt crisis. above all, the exodus of ball-hawking medical professionals has hit the island onerous. whereas quite 1/2 Puerto Rico's residents receive Medicare or health care, the island receives considerably fewer federal funds to acquire these programs than equally sized states on the dry land, like Mississippi.
This lack of funding combined with the island's dire monetary state of affairs precludes its ability to supply competitive compensation to doctors, nurses, and different medical workers. As a result, such professionals square measure effort the island as a group for a lot of remunerative opportunities on the dry land. during a report from CBS, the news outlet discusses some personal cases together with the story of Damarys Perales UN agency worked as Associate in Nursing controller in Puerto Rico's health department. Moreover, the country’s drain was conjointly exacerbated by cyclone Maria, that occurred Sept. 2, 2017, making even a lot of incentive for out-migration.
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Intracranial hemorrhage |
Intracranial hemorrhage (ICH), additionally referred to as intracranial bleed, is hemorrhage inside the bone. Subtypes ar neural structure bleeds (intraventricular bleeds and intraparenchymal bleeds), subarachnoid bleeds, epidural bleeds, and meninges bleeds.
Intracranial hemorrhage may be a serious medical emergency as a result of the buildup of blood inside the bone will result in will increase in intracranial pressure, which may crush delicate brain tissue or limit its blood provide. Severe will increase in intracranial pressure (ICP) will cause brain hernia, within which elements of the brain ar squeezed past structures within the bone.
Causes
Intracranial hemorrhage happens once a vessel inside the bone is damaged or leaks. It may result from physical trauma (as happens in head injury) or nontraumatic causes (as happens in trauma stroke) like a damaged cardiovascular disease. decoagulant medical aid, still as disorders with curdling will heighten the danger that AN intracranial hemorrhage can occur.
More than half all cases of intracranial hemorrhage is that the results of high blood pressure.
Diagnosis
An acute bleed into a long-standing cystic mass inside the brain. Arrow points to hemorrhage and mass.
CT scan (computed tomography) is that the definitive tool for correct diagnosing of AN intracranial hemorrhage.[citation needed] In tough cases, a 3T-MRI scan can even be used.
When ICP is inflated the center rate could also be shriveled.
The hemorrhage is taken into account a focal brain injury; that's, it happens in a very localized spot instead of inflicting diffuse harm over a wider space.
Intra-axial bleed
Main article: bleeding
Intra-axial hemorrhage is hemorrhage inside the brain itself, or bleeding. This class includes intraparenchymal hemorrhage, or hemorrhage inside the brain tissue, and cavum hemorrhage, hemorrhage inside the brain's ventricles (particularly of premature infants). Intra-axial hemorrhages ar a lot of dangerous and more durable to treat than extra-axial bleeds.[4]
Extra-axial bleed
Extra-axial hemorrhage, hemorrhage that happens inside the bone however outside of the brain tissue, falls into 3 subtypes:
Epidural hemorrhage (extradural hemorrhage) that occur between the meninges (the outer meninx) and therefore the bone, is caused by trauma. it should result from laceration of AN artery, most ordinarily the center arterial blood vessel. this is often a awfully dangerous sort of injury as a result of the bleed is from a hard-hitting system and deadly will increase in intracranial pressure may result quickly. However, it's the smallest amount common sort of tissue layer hemorrhage and is seen in I Chronicles to three cases of head injury.
Patients have a loss of consciousness (LOC), then a noticeable interval, then unforeseen deterioration (vomiting, restlessness, LOC)
Head CT shows biconvex (convex) deformity.
Subdural hemorrhage results from tearing of the bridging veins within the meninges area between the mama|meninx|meninges} and arachnoid mater.
Head CT shows lunate deformity
Subarachnoid hemorrhage (SAH), that occur between the arachnoid and herbaceous plant tissue layer layers, like intraparenchymal hemorrhage, may result either from trauma or from ruptures of aneurysms or blood vessel malformations. Blood is seen layering into the brain on sulci and fissures, or filling subarachnoid cisterns (most typically the bodily structure cistern as a result of the presence of the anterior cerebral arteries of the circle of Willis and their branchpoints inside that space). The classic presentation of subarachnoid hemorrhage is that the unforeseen onset of a severe headache (a thunderclap headache). SAH is taken into account a kind of stroke, despite technically being extra-axial. Confirmed spontaneous SAH needs any investigations on the supply of the hemorrhage, because the hemorrhage could recur while not intervention.
Epidural haematoma.
Epidural haematoma (EDH) may be a quickly accumulating haematoma between the meninges and therefore the bone. These patients have a history of head trauma with loss of consciousness, then a noticeable amount, followed by loss of consciousness. Clinical onset happens over minutes to hours. several of those injuries ar related to lacerations of the center arterial blood vessel. A "lenticular", or convex, lens-shaped extracerebral hemorrhage that doesn't cross suture lines can seemingly be visible on a CT scan of the pinnacle. though death may be a potential complication, the prognosis is sweet once this injury is recognized and treated.[citation needed]
Subdural hematoma
Main article: meninges haematoma
Subdural haematoma happens once there's tearing of the bridging vein between the neural structure and a debilitating duct. every now and then they will be caused by blood vessel lacerations on the brain surface. Acute meninges haematoma ar typically related to neural structure injury still and thence the prognosis isn't pretty much as good as further meninges haematoma. Clinical options rely on the positioning of injury and severity of injury. Patients could have a history of loss of consciousness however they recover and don't relapse. Clinical onset happens over hours. A crescent formed hemorrhage compression the brain that will cross suture lines are going to be noted on CT of the pinnacle. surgical process and surgical evacuation is needed if there's important pressure result on the brain.Complications embody focal neurological deficits looking on the positioning of haematoma and brain injury, inflated intracranial pressure resulting in hernia of brain and anaemia thanks to reduced blood provide and seizures.
Subarachnoid hemorrhage
Main article: Subarachnoid hemorrhage
A subarachnoid hemorrhage is hemorrhage into the subarachnoid space—the space between the meninges and therefore the meninx close the brain. Besides from head injury, it should occur ad lib, typically from a damaged aneurysm. Symptoms of SAH embody a severe headache with a fast onset (thunderclap headache), vomiting, confusion or a lowered level of consciousness, and generally seizures.[6] The diagnosing is usually confirmed with a CT scan of the pinnacle, or often by spinal puncture. Treatment is by prompt surgical process or radiologically target-hunting interventions with medications and alternative treatments to assist stop repeat of the hemorrhage and complications. Since the Nineties, several aneurysms ar treated by a bottom invasive procedure referred to as endovascular whorled, that is administrated by instrumentation through massive blood vessels. However, this procedure has higher repeat rates than the a lot of invasive surgical process with clipping.